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The broader concern about unapproved growth hormone peptides Eric Topol, writing in Ground Truths in July 2025, grouped ipamorelin with CJC-1295 and tesamorelin as growth hormone related peptides that "carry the potential risk of cancer" on mechanistic grounds, through IGF-1 elevation and broad cell growth signalling [4]

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The pattern repeats with dose increases: temporary return of sulfur burps for a week or two, gradual improvement, resolution or near-resolution by 3 to 4 weeks at the new dose

For a 180-pound (82 kg) person, that translates to roughly 98 to 123 grams of protein daily

While many of the findings are still new or based on small sample sizes, researchers are beginning to look more closely at how this medication influences sex drive, hormone levels, and overall sexual well-being